Publications

국외전문학술지

• 전체
• 2020
• 2019
• 2018
• 2017
• 2016
• 2015
• 2014
• 2013
• 2012
• 2011
• 2010
• 2009
• 2008
• 2007
• 2006
• 2005
• 2004
• 2003
• 2002
• 2001
• 2000
• 1999
• 1998
• 1997
• 1996
• 1995
• 1994
• 1993
• 1992

1. In vitro characterization of the thermoneutral transient receptor potential vanilloid-1 (TRPV1) inhibitor GRTE16523.

   Damann, N.; Bahrenberg, G.; Stockhausen, H.; Habermann, C. J.; Lesch, B.; Frank-Foltyn, R.; Lee, J.; Ann, J.; Christoph, T.

   Eur. J. Pharmacol. 2020, 871, 172934

   Mar 15, 2020
   Attachment file ; 187_EJP 2020 871 172934.pdf

2. Discovery of indane propanamides as potent and selective TRPV1 antagonists

   Ahn, S.; Kim, Y. S.; Kim, M. S.; Ann, J.; Ha, H.; Yoo, Y. D.; Kim, Y. H.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.

   Bioorganic & Medicinal Chemistry Letters 2020, 30, 126838.

   Feb 01, 2020
   Attachment file ; 186_BMCL 2020 30 126838.pdf

3. ​Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic

   Ann, J.; Ho Kim, H. S.; Thorat, S. A.; Hee Kim, Ha, H-J.; Choi, K.; Kim, Y-H.; Kim, M.; Hwang, S. W.; Pearce, L. V.; Esch, T. E.; Turcios, N. A.; Blumberg, P. M.; Lee, J.

   Journal of Medicinal Chemistry 2020, 63, 418-424.

   Jan 09, 2020
   Attachment file ; 185_JMC 2020 63 418.pdf

4. Functional Group-Dependent Induction of Astrocytogenesis and Neurogenesis by Flavone Derivatives

   Lee, H-R.; Kang, J. M.; Kim, Y. M.; Kim, S.; Ann, J.; Lee, J.; Kim, H-J.

   Biomolecules 2019, 9, 812.

   Dec, 2019

   
   Attachment file ; 184_B 2019 9 812.pdf

5. ​Differential effects of MEK inhibitors on rat neural stem cell differentiation: Repressive roles of MEK2 in neurogenesis and induction of astrocytogenesis by PD98059

   Lee, H-R.; Lee, J.; Kim, H-J.

   Pharmacological Reserch 2019, 149, 104466.

   Nov, 2019

   
   Attachment file ; 183_PR 2019 149 104466.pdf

6. ​Discovery of dual-acting opioid ligand and TRPV1 antagonists as novel therapeutic agents for pain

   Lee, H.; Ahn, S.; Ann, J.; Ha, H.; Yoo, Y. D.; Kim, Y. H.; Hwang, J-Y.; Hur, K-H. Jang, C-G.; Pearce, L. V.; Esch, T. E.; Lewin, N. E.; Blumberg, P. M.; Lee, J.

   European Journal of Medicinal Chemistry 2019, 182, 111634.

   Nov 15, 2019

   
   Attachment file ; 182_EJMC 2019 182 111634.pdf

7. In vitro and in silico determination of glutaminyl cyclase inhibitors

   Tran, P-T.; Hoang, V-H.; Lee, J.; T. T. T.; Tung, N. T.; Ngo, S. T

   RSC Advances 2019, 9, 29619-29627.

   Sep 19, 2019
   Attachment file ; 181_RSCA 2019 9 29619.pdf
8. 
   

   ​Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer’s Agents by Structure-Based Design

   Hoang, V-H.; Ngo, V. T. H.; Cui, M.; Manh, N. V.; Tran, P-T.; Ann, J.; Ha, H-J.; Kim, H.; Choi, K.; Kim, Y-H.; Chang, H.; Macalino, S. J. Y.; Lee, J.; Choi, S.; Lee, J.

   Journal of Medicinal Chemistry 2019, 62, 8011-8027.

   Sep 12, 2019 Attachment file ; 180_JMC 2019 62 8011.pdf
9. 
   

   Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level

   Pearce, L. V.; Ann, J.; Blumberg, P. M.; Lee, J.

   Biomolecules & Therapeutics 2019, 27(5), 435-441.

   Sep 01, 2019

   Attachment file ; 179_BT 2019 27 435.pdf
10. Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors
    Yoon, S.; Kim, J. H.; Kim, S-E.; Kim, C.; Tran, P-T.; Ann, J.; Koh, Y.; Jang, J.; Kim, S.; Moon, H-S; Kim, W. K; Lee, S.; Lee, J.; Kim, S.; Lee, J.
    Journal of Medicinal Chemistry 2016, 59(22), 10322–10328​
    Attachment file ; 155 JMC 2016 5922, 10322–10328.pdf

11. ​Differential Regulation of Gene Expression in Lung Cancer Cells by Diacyglycerol-Lactones and a Phorbol Ester Via Selective Activation of Protein Kinase C Isozymes

    Cooke, M.; Casado-Medrano, V.; Ann, J.; Lee, J.; Blumberg, P. M.; Abba, M. C.; Kazanietz, M. G.

    Scientific Reports 2019, 9, 6041

    April 15, 2019
    Attachment file ; 178_SR 2019 9 6041.pdf
12. 2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists
    Ann, J.; Ki, Y.; Yoon, S.; Kim, M. S.; Lee, J-U; Kim, C.; Lee, S.; Jung, A.; Baek, J.; Hong, S.; Choi, S.; Pearce, L. V.; Esch, T. E.; Turcios, N. A.; Lewin, N. E.; Ogunjirin, A. E.; Herold, B. K. A.; McCall, A. K.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry 2016, 24(6), 1231-1240.
    Attachment file ; 154 BMC 2016 24, 1231-1240.pdf
13. 
    

    ​C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.

    Cho, T-M.; Kim, J. Y.; Kim, Y-J.; Sung, D.; Oh, E.; Jang, S.; Farrand, L.; Hoang, V-H.; Nguyen, C-T; Ann, J.; Lee, J.; Seo, J. H.

    Cancer Letter 2019, 447, 141-153.

    April 10, 2019 Attachment file ; 177_CL 2019 447 141.pdf
14. Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity
    Lee, S-C.; Min, H-Y.; Choi, H.; Bae, S. Y.; Park, K. H.; Hyun, S. Y.; Lee, H. J.; Moon, J.; Park, S-H.; Kim, J. Y.; An, H.; Park, S-J.; Seo, J. H.; Lee, S.; Kim, Y-M.; Park, H-J.; Lee, S. K.; Lee, J.; Lee, J.; Kim, K-W.; Suh, Y-G.; Lee, H-Y.
    Cancer Research 2016, 76(3), 686-699​ Attachment file ; 153 Cancer Res. 2016 763, 686.pdf

15. Investigation of B,C-Ring Truncated Deguelin Derivatives as Heat Shock Protein 90 (HSP90) Inhibitors for Use as Anti-Breast Cancer Agents

    Kim, H. S.; Hoang, V-H.; Hong, M.; Kim, K. C.; Ann, J.; Nguyen, C-T.; Seo, J. H.; Choi, H.; Kim, J. Y.; Kim, K-W.; Byun, W. S.; Lee, S.; Lee, S.; Suh, Y-G.; Chen, J.; Park, H-J.; Cho, T-M.; Kim, J. Y.; Seo, J. H.; Lee, J.​

    Bioorganic & Medicinal Chemistry 2019, 27, 1370-1381.

    April 01, 2019

    Attachment file ; 176_BMC 2019 27 1370.pdf
16. Discovery of (S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase (LRS)-targeted mTORC1 inhibitor
    Yoon, S.; Kim, J. H.; Yoon, I.; Kim, C.; Kim, S-E; Koh, Y.; Jeong, S. J.; Lee, J.; Kim, S.; Lee J.
    Bioorganic & medicinal chemistry letters 2016, 26(13), 3038-3041
    Attachment file ; 152 BMCL 2016 26, 3038-3041.pdf

17. Structure-activity relationship of leucyladenylate sulfamate analogues asleucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target ofrapamycin complex 1 (mTORC1)

    Yoon, S.; Kim, S-E.; Kim, J. H.; Yoon, I.; Tran, P-T.; Ann, J.; Kim, C.; Byun, W. S.; Lee, S.; Kim, S.; Lee, J.; Lee, J.

    Bioorganic & Medicinal Chemistry 2019, 27, 1099-1109.

    Mar 15, 2019

    Attachment file ; 175_BMC 2019 27 1099.pdf
18. Discovery of a Small Molecule that Enhances Astrocytogenesis by Activation of STAT3, SMAD1/5/8, and ERK1/2 via Induction of Cytokines in Neural Stem Cells
    Lee, H-R.; Farhanullah; Lee, J.; Rahul, J.; Kong, S-Y.; Shin, J-Y; Kim, J-O.; Lee, J.; Lee, J.; Kim, H-J.
    ACS chemical neuroscience 2016, 7(1), 90-99
    
    Attachment file ; 151 ACS Chem. Neruosci. 2016, 71 90-99.pdf

19. Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

    An, H.; Lee, S.; Lee, J. M.; Jo, D. H.; Kim, J.; Jeong, Y-S.; Heo, M. J.; Cho, C. S.; Choi, H.; Seo, J. H.; Hwang, S.; Lim, J.; Kim, T.; Jun, H. O.; Sim, J.; Lim, C.; Hur, J.; Ahn, J.; Kim, H. S.; Seo, S-Y.; Na, Y.; Kim, S-H.; Lee, J.; Lee, J.; Chung, S-J.; Kim, Y-M.; Kim, K-W.; Kim, S. G.; Kim, J. M.; Suh, Y-G. ​

    Journal of Medicinal Chemistry 2018, 61, 9266-9286.

    Sep 25, 2018

    
    Attachment file ; 174. Journal of Medicinal Chemistry 2018, 61, 9266-9286.pdf
20. Discovery of an Orally Bioavailable Gonadotropin-Releasing Hormone Receptor Antagonist
    Kim, S-.M.; Lee, M.; Lee, S. Y.; Lee, S-M.; Kim, E. J.; Han, M. Y.; Yoo, T.; Park, E.; Ann, J.; Yoon, S.; Lee, J.
    Journal of medicinal chemistry 2016, 59(19), 9150-9172
    Attachment file ; 150 JMC 2016 5919, 9150-9172.pdf

21. Development of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer

    Hyun, S. Y.; Le, H. T.; Nguyen, C-T.; Yong, Y-S.; Boo, H-J.; Lee, H. J.; Lee, J-S.; Min, H-Y.; Ann, J.; Chen, J.; Park, H-J.; Lee, J.; Lee, H-Y.

    Scientific Reports 2018, 8, 13924

    Attachment file ; 173. Scientific Reports 2018, 8, 13924.pdf
22. Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template
    Ann, J.; Jung, A.; Baek, J.; Lee, S.; Kim, C.; Yoon, S.; Sun, W.; Zhou, X.; Hong, S.; Choi, S.; Turcios, N. A.; Herold, B. K. A.; Esch, T. E.; Lewin, N. E.; Abramovitz, A.; Pearce, L. V.; Blumberg, P. M.; Lee, J.
    Bioorganic & medicinal chemistry letters 2016, 26(15), 3603-3607​
    Attachment file ; 149 BMCL 2016 26, 3603-3607.pdf

23. Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1

    Lee, Y-H.; Song, N-Y.; Suh, J.; Kim, D-H.; Kim, W.; Ann, J.; Lee, J.; Baek, J-H.; Na, H-K.; Surh, Y-J.

    Cancer Letters 2018, 431, 219-229.

    Sep 01, 2018

    
    Attachment file ; 172. Cancer Letters 2018, 431, 219-229.pdf
24. Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors
    Kim, H. S.; Hong, M.; Ann, J.; Yoon, S.; Nguyen, C.-T.; Lee, S-C.; Lee, H-Y.; Suh, Y-G.; Seo, J. H.; Choi, H.; Kim, J. Y.; Kim, K-W.; Kim, J.; Kim, Y-M.; Park, S-J.; Park, H-J.; Lee, J.
    Bioorganic & medicinal chemistry 2016, 24(22), 6082-6093
    
    Attachment file ; 148 BMC 2016 24, 6082-6093.pdf

25. 4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands

    Kim, C.; Ann, J.; Lee, S.; Kim, E.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.

    Bioorganic & Medicinal Chemistry 2018, 26, 4509-4517.

    Aug 15, 2018

    
    Attachment file ; 171. BMC 2018 26, 4509-4517 Aug 15.pdf

26. Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors

    Yoon, S.; Zuo, D.; Kim, J. H.; Yoon, I.; Ann, J.; Kim, S-E.; Cho, D.; Kim, W. K.; Lee, S.; Lee, J.; Kim, S.; Lee, J.

    Bioorganic & Medicinal Chemistry 2018, 26, 4073-4079.

    Aug 07, 2018

    
    Attachment file ; 170. Bioorganic Medicinal Chemistry 2018, 26, 4073-4079.pdf
27. Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1a (HIF-1a) inhibitors.
    Kim, H. S.; Hong, M.; Lee, S-C.; Lee, H-Y.; Suh, Y-G.; Oh, D-C.; Seo, J. H.; Choi, H.; Kim, J. Y.; Kim, K-W.; Kim, J. H.; Kim, J.; Kim, Y-M.; Park, S-J.; Park, H-J.; Lee, J.
    European Journal of Medicinal Chemistry 2015, 104, 157-164. Attachment file ; 147. EJMC 2015 104, 157-164.pdf
28. Discovery of 2-(3,5-Difluoro-4-methylsulfonaminophenyl)propanamides as Potent TRPV1 Antagonists

    Kim, C.; Ann, J.; Lee, S.; Sun, W.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.

    Bioorganic & Medicinal Chemistry Letters 2018, 28, 2539-2542.

    Aug 01, 2018

    
    Attachment file ; 169. BMCL 2018 2814, 2539-2542 Aug 1.pdf
29. Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists
    Ann, J.; Jung, A.; Kim, M-Y.; Kim, H-M.; Ryu, H.; Kim, S.; Kang, D. W.; Hong, S.; Cui, M.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.
    Bioorganic & Medicinal Chemistry 2015, 23(21), 6844-6854 Attachment file ; 146. BMC 2015 23, 6844-6854.pdf

30. a-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands

    Ann, J.; Czikora, A.; Saini, A. S.; Zhou, X.; Mitchell, G. A.; Lewin, N. E.; Peach, M. L.; Blumberg, P. M.; Lee, J.​

    Journal of Medicinal Chemistry 2018, 61, 6261-6276.

    July 26, 2018

    
    Attachment file ; 168. Journal of Medicinal Chemistry 2018, 61, 6261-6276.pdf
31. 6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE)
    Choi, K.; Lim, K. S.; Shin, J.; Kim S. H.; Suh Y-G.; Hong H-S.; Kim, H.; Ha, H-J.; Kim, Y-H.;Lee, J.; Lee, J.
    Bioorganic & Medicinal Chemistry 2015, 23(15), 4919-4935 Attachment file ; 145. BMC 2015 23, 4919-4935.pdf

32. Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors

    Ngo, V, T.H.; Hoang, V-H.; Tran, P-T.; Manh, N. V.; Ann, J.; Kim, E.; Cui, M.; Choi, S.; Lee, J.; Kim, H.; Ha, H-J.; Choi, K.; Kim, Y-H.; Lee, J.

    Bioorganic & Medicinal Chemistry 2018, 26, 3133-3144.

    July 23, 2018

    
    Attachment file ; 167. Bioorganic Medicinal Chemistry 2018, 26, 3133-3144.pdf
33. Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90
    Lee, S-C.; Min, H-Y.; Choi, H.; Kim, H. S.; Kim, K-C.; Park, S-J.; Seong, M. A.; Seo, J. H.; Park, H-J.; Suh, Y-G.; Kim, K-W.; Hong, H-S.; Kim, H.; Lee, M-Y.; Lee, J.; Lee, H-Y.
    Molecular Pharmacology 2015, 88(2), 245-255 Attachment file ; 144. Mol Pharm 2015 882, 245-55.pdf

34. Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes

    Cooke, M.; Zhou, X.; Casado-Medrano, V.; Lopez-Haber, C.; Baker, M. J.; Garg, R.; Ann, J.; Lee, J.; Blumberg, P. M.; Kazanietz, M. G.

    J. Biol. Chem. 2018, 293(22), 8330-8341.

    June 1, 2018

    Attachment file ; 166. J. Biol. Chem. 2018, 29322, 8330-8341.pdf
35. An Aminopropyl Carbazole Derivative Induces Neurogenesis by Increasing Final Cell Division in Neural Stem Cells
    Shin, J-Y.; Kong, S-Y.; Yoon, H. J.; Ann, J.; Lee, J.; Kim, H-J.
    Biomolecules & Therapeutics 2015, 23(4), 313-319 Attachment file ; 143. Biomol Ther 2015 23, 313-319.pdf

36. Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells

    Hahn, Y-I.; Kim, S-J.; Choi, B-Y.; Cho, K-C.; Bandu, R.; Kim, K. P.; Kim, D-H.; Kim, W.; Park, J. S.; Han, B. W.; Lee, J.; Na, H-K.; Cha, Y-N.; Surh, Y-J.  

    Scientific Report 2018, 8(1), 6409

    April 23, 2018

    
    Attachment file ; 165. Scientific Report 2018, 81, 6409.pdf
37. a-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists
    Tran, P-T. Kim, H. S.; Ann, J.; Kim, S-E.; Kim, C.; Hong, M.; Hoang, V-H.; Ngo, V. T. H.; Hong, S.; Cui, M.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2015, 25(4), 2326-2330 Attachment file ; 142. BMCL 2015 25, 2326-2330.pdf

38. Comparative Effects of Curcumin and Tetrahydrocurcumin on Dextran Sulfate Sodium-induced Colitis and Inflammatory Signaling in Mice

    Yang, J-y.; Zhong, X.; Kim, S-J.; Kim, D-H.; Kim, H. S.; Lee, J-S.; Yum, H-W.; Lee, J.; Na, H-K.; Surh, Y-J.

    Journal of Cancer Prevention 2018, 23(1), 18-24

    Attachment file ; 164. Journal of Cancer Prevention 2018, 231, 18-24.pdf
39. Beyond the affinity for protein kinase C: exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands
    Rossi, D.; Talman, V.; Boije Af Gennäs, G.; Marra, A.; Picconi, P.; Nasti, R.; Serra, M.; Ann, J.; Amadio, M.; Pascale, A.; Tuominen, R. K.; Yli-Kauhaluoma, J.; Lee, J.; Collina, S.
    MedChemComm 2015, 6, 547-554 Attachment file ; 141. MedChemComm 2015 6, 547-554.pdf

40. Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region
    Ngo, V.T.H.; Hoang, V-H.; Tran, P-T.; Ann, J.; Cui, M.; Park, G.; Choi, S.; Lee, J.; Kim, H.; Ha, H-J.: Choi, K.; Kim, Y-H.; Lee, J.

    Bioorganic & Medicinal Chemistry 2018, 26(5), 1035-1049.

    Mar 01, 2018

     

     

     

     

    Attachment file ; 163. Bioorganic Medicinal Chemistry 2018, 265, 1035-1049.pdf
41. Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 Antagonists
    Ryu, H.; Seo, S.; Lee, J-Y.; Ha, T-H.; Lee, S.; Jung, A.; Ann, J.; Kim, S-E.; Yoon, S.; Hong, M.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Schiene, K.; Stockhausen, H.; Christoph, T.; Frormann, S.; Lee, J.
    European Journal of Medicinal Chemistry 2015, 93, 101-108 Attachment file ; 140. EJMC 2015 93, 101-108.pdf

42. Synthesis and biological evaluation of 3-(2-aminoethyl) uracil derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists

    Kim, S-M.; Lee, M.; Lee, S. Y.; Lee, S-M.; Kim, E. J.; Kim, J. S.; Ann, J.; Lee, J.; Lee, J.

    European Journal of Medicinal Chemistry 2018, 145, 413-424.

    Feb 10, 2018

     

     

     

     

     

    Attachment file ; 162. European Journal of Medicinal Chemistry 2018, 145, 413-424.pdf
43. Transient receptor potential vanilloid type 1 antagonists: a patent review (2011-2014)
    Lee, Y.; Hong, S.; Cui, M.; Sharma, P. K. Lee, J.; Choi, S.
    Expert Opinion on Therapeutic Patents 2015, 25(3), 291-318 Attachment file ; 139. Expert Opinion on Therapeutic Patents 2015 253, 291-318.pdf

44. Discovery of an Orally Bioavailable Benzofuran Analogue that Serves as a β-amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer’s Disease

    Ha, H-J.; Kang, D. W.; Kim, H-M.; Kang, K-M.; Ann, J.; Hyun, H. J.; Lee, J. H.; Kim, S. H.; Kim, H.; Choi, K.; Hong, H-S.; Kim, Y.; Jo, D-G.; Lee,J.; Lee, J.​

    Journal of Medicinal Chemistry 2018, 61, 396-402.

    Jan 11, 2018

     

     

     

    Attachment file ; 161. Journal of Medicinal Chemistry 2018, 61, 396-402.pdf
45. 6,6-Fused heterocyclic ureas as highly potent TRPV1 antagonists
    Sun, W.; Kim, H-S.; Lee, S.; Jung, A.; Kim, S-E.; Ann, J.; Yoon, S.; Choi, S.; Lee, J. H.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Schiene, K.; Stockhausen, H.; Christoph, T.; Frormann, S.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2015, 25(4), 803-806 Attachment file ; 138. BMCL 2015 254, 803-806.pdf

46. Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1)

    Pearce, L. V.; Ann, J.; Jung, A.; Thorat, S. A.; Herold, B. K. A.; Habtemichael, A. D.; Blumberg, P. M.; Lee, J.  

    Journal of Medicinal Chemistry 2017, 60(19), 8246-8252.

    Sep 11, 2017

     

     

     

     

     

    Attachment file ; 160. Journal of Medicinal Chemistry 2017, 6019, 8246-8252.pdf
47. Inhibition of Glutaminyl Cyclase Ameliorates Amyloid Pathology in an Animal Model of Alzheimer’s Disease via the Modulation of ramma-Secretase Activity
    Song, H.; Chang, Y. J.; Moon, M.; Park, S. K.; Tran, P-T.; Hoang, V-H.; Lee, J.; Mook-Jung, I.
    Journal of Alzheimer’s Disease 2015, 43(3), 797-807 Attachment file ; 137. Journal of Alzheimers Disease 2015 43, 797-807.pdf

48. Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

    Lee, S.; Kim, C.; Ann, J.; Thorat, S. A.; Kim, E.; Park, J.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J. Bioorganic & Medicinal Chemistry Letters 2016, 27(18), 4383-4388.

    Sep 15, 2017

    Attachment file ; 159. Bioorganic Medicinal Chemistry Letters 2016, 2718, 4383-4388.pdf
49. Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)
    Han, Y. T.; Kim, K.; Son, D.; An, H.; Kim, H.; Lee, J.; Park, H-J. Lee, J.; Suh, Y-G.
    Bioorganic & Medicinal Chemistry 2015, 23(3), 579-587 Attachment file ; 136. BMC 2015 23, 579-587 Feb 1.pdf
50. 
    

    Discovery of Simplified Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors.

    Yoon, S.; Kim, J. H.; Koh, Y.; Tran, P-T.; Ann, J.; Yoon, I.; Jang, J.; Kim, W. K.; Lee, S.; Lee, J.; Kim, S.; Lee, J.

    ​

     

     

     

    ​

    Bioorganic & Medicinal Chemistry 2017, 25(15), 4145-4152.

    Aug 01, 2017

     

     

     

    Attachment file ; 158. Bioorganic Medicinal Chemistry 2017, 2515, 4145-4152.pdf
51. Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones)
    Ann, J.; Yoon, S.; Baek, J.; Kim, D. H.; Lewin, N. E.; Hill, C. S.; Blumberg, P. M.; Lee, J.
    European Journal of Medicinal Chemistry 2015, 90, 332-341 Attachment file ; 135. EJMC 2015 90, 332-341 Jan 27.pdf
52. 
    

    t-Butyl Pyridine and Phenyl C-region Analogues of 2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as Potent TRPV1 Antagonists

    Lee, S.; Kang, D. W.; Ryu, H.; Kim, C.; Ann, J.; Lee, H.; Kim, E.; Hong, S.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Christoph, T.; Lee, J.

    ​

     

     

     

     

    ​

    Bioorganic & Medicinal Chemistry 2017, 25(8), 2451-2462.

    Apr 15, 2017

     

     

     

     

    Attachment file ; 157. Bioorganic Medicinal Chemistry 2017, 258, 2451-2462.pdf
53. 
    

    Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents based on Rational Design

     Hoang, V-H.; Tran, P-T.; Cui, M.; Van T.H. Ngo, V.T.H.; Ann, J.; Park, J.; Lee, J.; Choi, K.; Cho, H.; Kim, H.; Ha, H-J.; Hong, H-S.; Choi, S.; Kim, Y-H.; Lee, J.

    Journal of Medicinal Chemistry 2017, 60(6), 2573-2590.

    Mar 23, 2017

     

     

     

     

     

     

     

     

    Attachment file ; 156. Journal of Medicinal Chemistry 2017, 606, 2573-2590..pdf
54. Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors.
    Jo, D. H.; An, H.; Chang, D-J.; Baek, Y-Y.; Cho, C. S.; Jun, H. O.; Park, S-J.; Kim, J. H.; Lee, H-Y.; Kim, K-W.: Lee, J.; Park, H-J.; Kim, Y-M.; Suh, Y-G.; Kim, J. H.
    Journal of Molecular Medicine (Beri) 2014, 92(10), 1083-1092. Attachment file ; 134. Journal of Molecular Medicine 2014 9210, 1083-1092.pdf
55. 2-Aryl Substituted Pyridine C-region Analogues of 2-(3-Fluoro-4-methylsulfonylaminophenyl) propanamides as Highly Potent TRPV1 Antagonists
    Ryu, H.; Seo, S.; Kim, M. S.; Kim, M-Y.; Kim, H. S.; Ann, J.; Tran, P-T.; Hoang, V-H.; Byun, J.; Cui, M.; Son, K.; Sharma, P. K.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Koegel, B-Y.; Christoph, T.; Frormann, S.; Lee. J.
    Bioorganic & Medicinal Chemistry Letters 2014, 24(16), 4044-4047. Attachment file ; 133. BMCL 2014 24, 4044-4047.pdf
56. 2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylamino phenyl)propanamides as highly potent TRPV1 antagonists
    Ryu, H.; Seo, S.; Cho, S-H.; Kim, H. S.; Jung, A.; Kang, D. W.; Son, K.; Cui, M.; Hong, S-h.; Sharma, P. K.; Choi, S.; Blumberg, P. M.; Frank-Foltyn, R.; Bahrenberg, G.; Stockhausen, H.; Schiene, K.; Christoph, T.; Frormann, S.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2014, 24(16), 4039-4043. Attachment file ; 132. BMCL 2014 24, 4039-4043.pdf
57. Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis.
    Choi, Y. J.; Yoon, Y.; Lee, K. Y.; Hien, T. T.; Kang, K. W.; Kim, K. C.; Lee, J.; Lee, M. Y.; Lee, S. M.; Kang, D. H.; Lee, B. H.
    FASEB J 2014, 28(7), 3197-3204 Attachment file ; 131. FASEB J 2014 28, 3197-3204.pdf
58. α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists.
    Kim, H. S.; Jin, M-K.; Kang, S-U.; Lim, J-O.; Tran, P-T.; Hoang, V-H.; Ann, J.; Ha, T-H.; Pearce, L. V.; Pavlyukovets, V. A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2014, 24(12), 2685-2688. Attachment file ; 130. BMCL 2014 24, 2685-2688.pdf
59. Migration of neutrophils targeting amyloid plaques in Alzheimer’s disease mouse model.
    Baik, S. H.; Cha, M-Y.; Hyun, Y-M.; Cho, H.; Hamza, B.; Kim, D. K.; Han, S-H.; Choi, H.; Kim, K. H.; Moon, M.; Lee, J.; Kim, M.; Irimia, D.; Mook-Jung, I.
    Neurobiology of Aging 2014, 35, 1286-1292. Attachment file ; 129. Neurobiology of Aging 2014 35, 1286-1292.pdf
60. Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products(RAGE).
    Han, Y. T.; Kim, K.; Choi, G-I.; An, H.; Son, D.; Kim, H.; Ha, H-J.; Son, J-H.; Chung, S-J.; Park, H-J.; Lee, J.; Suh, Y-G.
    European Journal of Medicinal Chemistry 2014, 79, 128-142. Attachment file ; 128. EJMC 2014 79, 128-142.pdf
61. Asymmetric Synthesis and Receptor Activity of Chiral Simplified Resiniferatoxin (sRTX) Analogues as Transient Receptor Potential Vanilloid 1 (TRPV1) Ligands.
    Kim, M. S.; Ki, Y.; Ahn, S. Y.; Yoon, S.; Kim, S-E.; Park, H-G.; Sun, W.; Son, K.; Cui, M.; Choi, S.; Pearce, L. V.; Esch, T. E.; DeAndrea-Lazarus, I. A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2014, 24(1), 382-385 Attachment file ; 127. BMCL 2014 24, 382-385.pdf
62. Aminopropyl carbazole analogues as potent enhancers of neurogenesis.
    Yoon, H. J.; Kong, S-Y.; Park, M-H.; Cho, Y.; Kim, S-E.; Shin, J-Y.; Jung, S.; Lee, J.; Farhanullah, Kim, H-J.; Lee, J.
    Bioorganic & Medicinal Chemistry 2013, 21(22), 7165-7174. Attachment file ; 126. BMC 2013 21, 7165-7174.pdf
63. TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides.
    Ha, T-H, Ryu, H.; Kim, S-E.; Kim, H. S.; Ann, J.; Tran, P-T.; Hoang, V-H.; Son, K.; Cui, M.; Choi, S.; Blumberg, P. M.; Frank, R.; Bahrenberg, G.; Schiene, K.; Christoph, T.; Frormann, S.; Lee, J.
    Bioorganic & Medicinal Chemistry 2013, 21(21), 6657-6664. Attachment file ; 125. BMC 2013 21, 6657-6664.pdf
64. The carbonate analogues of 5’-halogenated resiniferatoxin as TRPV1 ligands.
    Lim, K. S.; Lee, H.; Kim, S-E.; Ha, T-H.; Ann, J.; Son, K.; Choi, S.; Sun, W.; Pearce, L. V.; DeAndrea-Lazarus, I. A.; Blumberg, P. M.; Lee, J.
    European Journal of Medicinal Chemistry 2013, 68, 233-243. Attachment file ; 124. EJMC 2013 68, 233-243.pdf
65. Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template.
    Tran, P-T.; Hoang, V-H.; Thorat, S. A.; Kim, S. E.; Ann, J.; Chang, Y. J.; Nam, D. W.; Song, H.; Mook-Jung, I.; Lee, J.; Lee, J.
    Bioorganic & Medicinal Chemistry 2013, 21(13), 3821-3830. Attachment file ; 123. BMC 2013 21, 3821-3830.pdf
66. 2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region.
    Thorat, S. A.; Kang, D. W.; Ryu, H.; Kim, M. S.; Kim, H. S.; Ann, J.; Ha, T.; Kim, S-E.; Son, K.; Choi, S.; Blumberg, P. M.; Frank, R.; Bahrenberg, G.; Schiene, K.; Christoph, T.; Lee, J.
    European Journal of Medicinal Chemistry 2013, 64, 589-602. Attachment file ; 122. EJMC 2013 64, 589-602.pdf
67. A two-photon fluorescent probe for amyloid-beta plaques in living mice.
    Heo, C. H.; Kim, K. H.; Kim, H. J.; Baik, S. H.; Song, J.; Kim, Y. S.; Lee, J.; Mook-jung, I.; Kim, H. M.
    Chemical Communications 2013, 49(13), 1303-1305. Attachment file ; 121. ChemComm 2013 49, 1303-1305.pdf
68. Ligand-Based Design, Synthesis, and Biological Evaluation of 2-Aminopyrimidines, a Novel Series of Receptor for Advanced Glycation End Products (RAGE) Inhibitors.
    Han, Y. T.; Choi, G-I.; Son, D.; Kim, N-J.; Yun, H.; Lee, S.; Chang, D. J.; Hong, H-S.; Kim, H.; Ha, H-J.; Kim, Y-H.; Park, H-J.; Lee, J.; Suh, Y-G.
    Journal of Medicinal Chemistry 2012, 55(21), 9120-9135. Attachment file ; 120. JMC 2012 55, 9120-9135.pdf
69. 2-(3-Fluoro-4-methylsulfonylaminophenyl) Propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure Activity Relationships of 2-Amino Derivatives in the N-(6-trifluoromethyl-pyridin-3-ylmethyl) C-region.
    Kim, M. S.; Ryu, H.; Kang, D. W.; Cho, S-H.; Seo, S.; Park, Y. S.; Kim, M-Y.; Kwak, E. J.; Kim, Y. S.; Bhondwe, R. S.; Kim, H. S.; Park, S-g. Son, K.; Choi, S.; DeAndrea-Lazarus, I.; Pearce, L. V.; Blumberg, P. M.; Frank, R.; Bahrenberg, G.; Stockhausen, H.; Kogel, B. Y.; Schiene, K.; Christoph, T.; Lee, J.
    Journal of Medicinal Chemistry 2012, 55(19), 8392-8408. Attachment file ; 119. JMC 2012 5519, 8392-8408.pdf
70. The SAR analysis of TRPV1 agonists with the α-methylated B-region.
    Cho, Y.; Kim, M. S.; Kim, H. S.; Ann, J.; Lee, J.; Pearce, L. V.; Pavlyukovets, V. A.; Morgan, M. A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2012, 22(16), 5227-5231 Attachment file ; 118. BMCL 2012 22, 5227-5231.pdf
71. Structure activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N’-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism.
    Bhondwe, R. S.; Kang, D. W.; Kim, M. S.; Kim, H. S.; Park, S-G.; Son, K.; Choi, S.; Lang Kuhs, K. A.; Pavlyukovets, V. A.; Pearce, L. V.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2012, 22(11), 3656-3660. Attachment file ; 117. BMCL 2012 22, 3656-3660.pdf
72. Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease.
    Moon, M.; Hong, H-S.; Nam, D. W.; Baik, S. H.; Song, H.; Kook, S-Y.; Kim, Y.; Lee. J., Mook-Jung, I.
    Journal of Alzheimer’s Disease 2012, 29(3), 615-628. Attachment file ; 116. Journal of Alzheimers Disease 2012 29, 615-628.pdf
73. Transient Receptor Potential Vanilloid-1 (TRPV1) Is a Mediator of Lung Toxicity for Coal Fly Ash Particulate Material.
    Deering-Rice, C. E.; Johansen, M. E.; Roberts, J. K.; Thomas, K. C.; Romero, E. G.; Lee, J.; Yost, G. S.; Veranth, J. M.; Reilly, C. A.
    Molecular Pharmacology 2012, 81(3), 411-419. Attachment file ; 115. Mol Pharm 2012 81, 411-419.pdf
74. 2-(4-Methylsulfonylaminophenyl) Propanamide TRPV1 Antagonists: Structure Activity Relationships in the B and C-regions.
    Sun, W.; Liu, K.; Ryu, H.; Kang, D. W.; Kim, Y. S.; Kim, M. S.; Cho, Y.; Bhondwe, R. S.; Thorat, S. A.; Kim, H. S.; Pearce, L. V.; Pavlyukovets, V. A.; Tran, R.; Morgan, M. A.; Lazar, J.; Ryder, C. B.; Toth, A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry 2012, 20(3), 1310-1318. Attachment file ; 114. BMC 2012 20, 1310-1318.pdf
75. N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the A-region.
    Kim, Y. S.; Kil, M-J.; Kang, S-U.; Ryu, H.; Kim, M. S.; Cho, Y.; Bhondwe, R. S.; Thorat, S. A.; Sun, W.; Liu, K.; Lee, J. H.; Choi, S.; Pearce, L. V.; Pavlyukovets, V. A.; Morgan, M. A.; Tran, R.; Lazar, J.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry 2012, 20(1), 215-224. Attachment file ; 113. BMC 2012 20, 215-224.pdf
76. Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury
    American Journal of Physiology - Lung Cellular and Molecular.
    Thomas, K. C.; Roberts, J. K.; Deering-Rice, C. E.; Romero, E. G.; Dull, R. O.; Lee, J.; Yost, G. S.; Reilly, C. A.
    Physiology 2012, 302(1), L111-L119. Attachment file ; 112. Am J Physio - Lung cell and Mol Physio 2012 3021 L111-L119 .pdf
77. Physiologically based pharmacokinetic modeling of SNU-0039, an anti-Alzheimer’s agent, in rats.
    Lee, K-R. Chae, Y-J.; Maeng, H-J.; Lee, J.; Kim, D-D.; Chong, S.; Shim, C-K.; Suk-Jae Chung, S-J.
    J. Pharmacokinet. Pharmacodyn. 2011, 38(5), 637-651. Attachment file ; 111. J Pharmacokinet Pharmacodyn 2011 385, 637-651.pdf
78. ​TRPV1 activation is not an all-or-none event: TRPV1 partial agonism/antagonism and its regulatory modulation
    Blumberg, P. M.; Pearce, L. V.; Lee, J.  
    Current Topics in Medicinal Chemistry 2011, 11(17), 2151-2158.​ Attachment file ; 110. Current Topics in Med Chem 2011 11, 2151-2158.pdf
79. Structure Activity Relationship of Capsaicin Analogs and Transient Receptor Potential Vanilloid 1-Mediated Human Lung Epithelial Cell Toxicity​
    Thomas, K. C.; Ethirajan, M.; Shahrokh, K.; Sun, H.; Lee, J.; Cheatham III, T. E.; Yost, G. S.; Reilly. C. A. 
    Journal of Pharmacology and Experimental Therapeutics J. Pharmacol. Exp. Ther. (JPET) 2011, 337(2), 400-410.
    Attachment file ; 109. JPET 2011 337, 400-410.pdf
80. ​Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies​
    Lee, J. H.; Lee, Y.; Ryu, H.; Kang, D. W.; Lee, J.; Lazar, J.; Pearce, L. V.; Pavlyukovets, V. A.; Blumberg, P. M.; Choi, S.  
    Journal of Computer-Aided Molecular Design 2011, 25(4), 317-327.​ Attachment file ; 108. J Comput Aided Mol Des 2011 25, 317-327.pdf
81. Inhibition of LXRα-dependent steatosis and oxidative injury by liquiritigenin, a licorice flavonoid, as mediated with Nrf2 activation.​
    Kim, Y. W.; Kim, Y. M.; Yang, Y. M.; Kay, H. Y.; Kim, W. D.; Lee, J. W.; Hwang, S. J.; Kim, S. G.
    Antioxidants & Redox Signaling 2011, 14(5), 733-745​ Attachment file ; 107. Antioxidants Redox Signalling 2011 733.pdf
82. ​ Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats​
    Kang, H. E.; Sohn, S. I.; Baek, S. R.; Lee, J.; Lee, M. G.
    Journal of Pharmacy and Pharmacology 2011, 63(1), 49-57​ Attachment file ; 106. Journal of Pharmacy and Pharmacology 2011 63, 49-57.pdf
83. Receptor Activity and Conformational Analysis of 5’-Halogenated Resiniferatoxin Analogues as TRPV1 Ligands​
    Lim, K. S.; Kang, D. W.; Kim, Y. S.; Kim, M. S.; Park, S-G.; Choi, S.; Pearce, L. V.; Blumberg, P. M.; Lee, J. 
    Bioorganic & Medicinal Chemistry Letters 2011, 21(1), 299-302​ Attachment file ; 105. BMCL 2011 21, 299-302.pdf
84. Halogenation of 4-Hydroxy/Amino-3-methoxyphenyl Acetamide TRPV1 Agonists Showed Enhanced Antagonism to Capsaicin​
    Kang, D. W.; Kim, Y. S.; Lim, K. S.; Kim, M. S.; Pearce, L. V.; Pavlyukovets, V. A.; Tao, A. K.; Lang-Kuhs, K. A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry 2010, 18(22), 8092-8105.​ Attachment file ; 104. BMC 2010 8092-8105.pdf
85. Liquiritigenin pharmacokinetics in a rat model of diabetes mellitus induced by streptozotocin: greater formation of glucuronides in the liver, especially M2, due to increased hepatic uridine 5′-diphosphoglucuronic acid level. ​
    Kang, H. E.; Sohn, S. I.; Baek, S. R.; Lee, J. W.; Lee, M. G.
    Metabolism 2010, 59(10), 1472-1480​ Attachment file ; 103. Metabolism 2010 59, 1472-1480.pdf
86. Pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats with acute hepatitis induced by d-galactosamine/lipopolysaccharide or CCl4 ​
    Kang, H. E.; Kim, Y. W.; Sohn, S. I.; Baek, S. R.; Lee, J. W.; Kim, S. G.; Lee, I.; Lee, M. G.
    Xenobiotica 2010, 40(6), 424-436​ Attachment file ; 102. Xenobiotica 2010 40, 424-436.pdf
87. Pharmacokinetic interaction between liquiritigenin (LQ) and DDB: Increased glucuronidation of LQ in the liver possibly due to increased hepatic blood flow rate by DDB​
    Kang, H. E.; Chung, H. J.; Kim, H. S.; Lee, J. W.; Lee, M. G. 
    European Journal of Pharmaceutical Sciences 2010, 39(3), 181-189​ Attachment file ; 101. EJPS 2010 39, 181-189.pdf
88. Polar 3-alkylidene-5-pivaloyloxymethyl-5’-hydroxymethyl--lactones as protein kinase C ligands and antitumor agents​
    Kang, J-H.; Kim, Y.; Won, S-H.; Park, S-K, Lee, C. W., Kim, H-M.; Lewin, N. E.; Perry, N. A.; Pearce, L. V.; Lundberg, D. J.; Surawski, R. J.; Blumberg, P. M. Lee, J. 
    Bioorganic & Medicinal Chemistry Letters 2010, 20(3), 1008-1012​ Attachment file ; 100. BMCL 2010 1008-1012.pdf
89. Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists ​
    Choi, H-K.; Choi, S.; Lee, Y.; Kang, D. W.; Ryu, H.; Maeng, H-J.; Chung, S-J.; Pavlyukovets, V. A.; Pearce, L. V.; Toth, A.; Tran, R.; Wang, Y.; Morgan, M. A.; Blumberg, P. M.; Lee, J.
    Bioorganic & Medicinal Chemistry 2009, 17(2), 690-698.​ Attachment file ; 99. BMC 2009 17, 690-698.pdf
90. Conformationally constrained analogues of N′-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl) thiourea as TRPV1 antagonists​
    Lim, J-O.; Jin, M-K.; Ryu, H.; Kang, D. W.; Lee, J.; Pearce, L. V.; Tran, R.; Toth, A.; Blumberg, P. M. 
    European Journal of Medicinal Chemistry 2009, 44(1), 322-331.​ Attachment file ; 98. EJMC 2009 44. 322-331.pdf
91. 2-[2-Substituted-3-(3,4-dichlorobenzylamino)propylamino]-1H-quinolin-4-ones as Staphylococcus aureus methionyl-tRNA synthetase inhibitors​
    Farhanullah; Kang, T.; Yoon, E-J.; Choi, E-C.; Kim, S.; Lee, J.
    European Journal of Medicinal Chemistry 2009, 44(1), 239-250.​ Attachment file ; 97. EJMC 2009 44, 239-250.pdf
92. Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X and TRPV1​.
    Light, A.; Hughen, R.; Zhang, J.; Rainier, J.; Liu, Z.; Lee, J.
    Journal of Neurophysiology 2008, 100(3), 1184-1201.​ Attachment file ; 96. J Neurophysiology 2008 1003 1184-1201.pdf
93. Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective iological Activities.​
    Duan, D.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Kedei, N.; Peach, M. L.; Lee, J.; Abeyweera, T. P.; Rotenberg, S. A.; Kim, H.; Kim, Y. H.; Kazzouli, S. E.; Chung, J-U.; Young, H. A.; Young, M. R.; Baker, A.; Colburn, N. H.; Haimovitz-Friedman, A.; Truman, J-P.; Parrish, D. A.; Deschamps, J. R.; Perry, N. A.; Surawski, R. J.; Blumberg, P. M.; Marquez, V. E.
    Journal of Medicinal Chemistry 2008, 51(17), 5198-5220.​ Attachment file ; 95. JMC 2008 51, 5198-5220.pdf
94. Differential modulation of vanilloid structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors​
    Pearce,L. V.; Toth, A.; Ryu, H.; Kang, D. W.; Choi, H-K.; Jin, M-K.; Lee, J.; Blumberg, P. M. 
    Naunyn Schmiedeberg’s Archieves of Pharmacology 2008, 377(2), 149-157.​ Attachment file ; 94. Naunyn-Schmiedebergs Arch Pharmacol 2008 149.pdf
95. Stereospecific High-affinity TRPV1 Antagonists: Chiral N-(2-Benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide Analogues
    Ryu, H.; Jin, M-K.; Kang, S-U.; Kim, S. Y.; Kang, D. W.; Lee, J.; Pearce, L. V.; Pavlyukovets, V. A.; Morgan, M. A.; Tran, R.; Toth, A.; Lundberg, D. J.; Blumberg, P. M.  
    Journal of Medicinal Chemistry 2008, 51(1), 57-67.​ Attachment file ; 93. JMC 2008 51, 57-67.pdf
96. a-Substituted N-(4-tert-butylbenzyl)-N’-[4-(methylsulfonylamino)-benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists
    Chung, J-U.; Kim, S. Y.; Lim, J-O.; Choi, H-K, Kang, S-U.; Yoon, H-S.; Ryu, H.; Kang, D. W.; Lee, J.; Kang, B.; Choi, S.; Toth, A.; Pearce, L. V.; Pavlyukovets, V. A.; Lundberg, D. J.; Blumberg, P. M. 
    Bioorganic & Medicinal Chemistry 2007, 15(18), 6043-6053.​ Attachment file ; 92. BMC 2007 15, 6043-6053.pdf
97. Halogenation of 4-hydroxy-3-methoxybenzyl thiourea TRPV1 agonists showed enhanced antagonism to capsaicin​
    Kang, D. W.; Ryu, H.; Lee, J.; Krystle A. Lang, K. A.; Pavlyukovets, V. A.; Pearce, L. A.; Ikeda, T.; Lazar, J.; Blumberg, P. M.
    Bioorganic & Medicinal Chemistry Letters 2007, 17(1), 214-219​ Attachment file ; 91. BMCL 2007 17, 214-219.pdf
98. Design and synthesis of quinolinones as methionyl-tRNA synthetase inhibitors​
    Farhanullah, Kim, S. Y.; Yoon, E-J.; Choi, E-C.; Kim, S.; Kang, T.; Samrin, F, Puri, S.; Lee, J.
    ioorganic & Medicinal Chemistry 2006, 14(21), 7154-7159.​ Attachment file ; 90. BMC 2006 7154.pdf
99. Pharmacophore-based virtual screening: The discovery of novel methionyl-tRNA synthetase inhibitors​
    Kim, S. Y.; Lee, Y-S.; Kang, T.; Kim, S.; Lee, J.
    Bioorganic & Medicinal Chemistry Letters 2006, 16(18), 4898-4907.​ Attachment file ; 89. BMCL 2006 4898.pdf
100. Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.​
     Lazar, J.; Braun, D. C.; Toth, A.; Wang, Y.; Pearce, L. V.; Pavlyukovets, V. A.; Blumberg, P. M.; Garfield, S. H.; Wincovitch, S.; Choi, H-K.; Lee, J.
     Molecular Pharmacology 2006, 69(4), 1166-1173.​ Attachment file ; 88. Mol Pharm 2006 1166.pdf
101. ​Branched Diacylglycerol-lactones as Potent Protein Kinase C Ligands and a-Secretase Activators.​
     Lee, J.; Kang, J-H.; Han, K-C.; Kim, Y.; Kim, S. Y.; Youn, H-S.; Mook-Jung, I.; Kim, H.; Han, J. H. L.; Ha, H. J.; Kim, Y. H.; Marquez, V. E.; Lewin, N. E.; Pearce, L. V.; Lundberg, D. J.; Blumberg, P. M.
     Journal of Medicinal Chemistry 2006, 49(6), 2028-2036.​ Attachment file ; 87. JMC 2006 2028.pdf
102. 2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands.
     Lee, J.; Lee, J-H.; Kim, S. Y.; Perry, N. A.; Lewin, N. E.; Ayres, J. A.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry 2006, 14(6), 2022-2031.​ Attachment file ; 86. BMC 2006 2022.pdf
103. Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells.​
     Reilly, C. A.; Johansen, M. E.; Lanza, D. L.; Lee, J.; Lim, J-O.; Yost, G. S.
     Journal of Biochemical and Molecular Toxicolgy 2005, 19(4), 266-275.​ Attachment file ; 85. JBMT 2005 266.pdf
104. Analysis of Structure Activity Relationships for the “B-region” of N-(4-t-Butylbenzyl)-N’-[4-(methylsulfonylamino)benzyl]thiourea Analogues as TRPV1 Antagonists. ​
     Lee, J.; Jin, M-K.; Kang, S-U.; Kim, S. Y.; Lee, J.; Shin, M.; Hwang, J.; Cho, S.; Choi, Y-S.; Choi, H-K.; Kim, S-E.; Suh, Y-G.; Lee, Y-S.; Kim, Y-H.; Ha, H-J.; Toth, A.; Pearce, L. V.; Tran, R.; Szabo, T.; Welter, J. D.; Lundberg, D. J.; Wang, Y.; Lazar, J.; Pavlyukovets, V. A.; Morgan, M. A.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry Letters 2005, 15(18), 4143-4150.​ Attachment file ; 84. BMCL 2005 4143.pdf
105. Analysis of Structure Activity Relationships for the “A-region” of N-(4-t-Butylbenzyl)-N’-[4-(methylsulfonylamino)benzyl]thiourea Analogues as TRPV1 Antagonists. ​
     Lee, J.; Kang, S-U.; Kil, M-J.; Shin, M.; Lim, J-O.; Choi, H-K.; Jin, M-K.; Kim, S. Y.; Kim, S-E.; Lee, Y-S.; Min, K-H.; Kim, Y-H.; Ha, H-J.; Tran, R.; Welter, J. D.; Wang, Y.; Szabo, T.; Pearce, L. V.; Lundberg, D. J.; Toth, A.; Pavlyukovets, V. A.; Morgan, M. A.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry Letters 2005, 15(18), 4136-4142​ Attachment file ; 83. BMCL 2005 4136.pdf
106. N​ovel Potent Antagonists of Transient Receptor Potential Channel, Vanilloid Subfamily Member 1: Structure-Activity Relationship of 1,3-Diarylalkyl Thioureas Possessing New Vanilloid Equivalents.​Suh, Y-G.; Lee, Y-S; Min, K-H.; Park, O-H.; Kim, J-K.; Seung, H-S.; Seo, S-Y.; Lee, B-Y.; Nam, Y-H.; Lee, K-O.; Kim, H-D.; Park, H-G.; Lee, J.; Oh, U.; Ju-Ok Lim, Kang, S-U.; Kil, M-J.; Koo, J-Y.; Shin, S. S.; Joo, Y-H.; Kim, J. K.; Jeong, Y-S.; Kim, S-Y.; Park, Y-H. 
     Journal of Medicinal Chemistry 2005, 48(18), 5823-5836.​ Attachment file ; 82. JMC 2005 5823-5836.pdf
107. Deoxyribosyl Analogues of Methionyl and Isoleucyl Sulfamate Adenylates as Inhibitors of Methionyl-tRNA and Isoleucyl-tRNA Synthetases.​
     Kim, S. E.; Kim, S. Y.; Kim, S.; Kang, T.; Lee, J.
     Bioorganic & Medicinal Chemistry Letters 2005, 15(14), 3389-3393.​ Attachment file ; 81. BMCL 2005 3389-3393.pdf
108. ​Different Vanilloid Agonists Cause Different Patterns of Calcium Response in CHO Cells Heterologously Expressing Rat TRPV1. ​
     Toth, A.; Wang, Y.; Kedei, N.; Tran, R.; Pearce, L. V.; Kang, S-U.; Jin, M-K.; Choi, H-K.; Lee, J.; Blumberg, P. M.
     Life Sciences 2005, 76(25), 2921-2932.​ Attachment file ; 80. Life Science 2005 2921-2932.pdf
109. ​Synthesis and Evaluation of Fluorine-substituted 1H-Pyrrolo[2,3-b]pyridine Derivatives for Dopamine D4 Receptor Imaging. ​
     Oh, S-J.; Lee, K. C.; Lee, S-Y.; Ryu, E. K.; Saji, H.; Choe, Y. S.; Chi, D. Y.; Kim, S. E.; Lee, J.; Kim, B-T.  
     Bioorganic & Medicinal Chemistry 2004, 12(21), 5505-5513.​ Attachment file ; 79. BMC 2004 5505-5513.pdf
110. Conformationally Constrained Analogues of Diacylglycerol. 24. Asymmetric Synthesis of a Chiral (R)-DAG-Lactone Template as a Versatile Precursor for Highly Functionalized DAG-Lactones.​
     Kang, J-H.; Siddiqui, M. A.; Lewin, N. E.; Pu, Y.; Sigano, D. M.; Blumberg, P. M.; Lee, J.; Marquez, V. E.
     Organic Letters 2004, 6(14), 2413-2416.​ Attachment file ; 78. OL 2004 2413-2416.pdf
111. Macrocyclic DAG-bis-Lactones as Conformationally Constrained Analogues of Diacylglycerol-Lactones (DAG-Lactones). Interactions with Protein Kinase C (PKC).​
     Kang, J-H.; Kim, S. Y.; Lee, J.; Marquez, V. E.; Lewin, N. E.; Pearce, L. V.; Blumberg, P. M.
     Journal of Medicinal Chemistry 2004, 47(16), 4000-4007.​ Attachment file ; 77. JMC 2004 4000-4007.pdf
112. Analysis of structure activity relationships with the N-(3-acyloxy-2-benzylpropyl)-N’-[4-(methylsulfonylamino)benzyl]thiourea template for vanilloid receptor 1 antagonism​
     Lee, J.; Kim, S. Y.; Lee, Ji.; Kang, M.; Kil, M-J.; Choi, H-K.; Jin, M-K.; Wang, Y.; Toth, A.; Pearce, L. V.; Lundberg, D. J.; Tran, R.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry 2004, 12(13), 3411-3420.​ Attachment file ; 76. BMC 2004 3411-3420.pdf
113. 3D-QSAR Analysis of Conformationally Constrained Diacylglycerol (DAG) Analogues as Potent Protein Kinase C (PK-C) Ligands.
     Kim, S. Y.; Lee, J.  
     Bioorganic & Medicinal Chemistry 2004, 12(10), 2639-2644.
     Attachment file ; 75. BMC 2004 2639-2644.pdf
114. Analysis of Structure–Activity Relationships for the `B-region' of N-(3-Acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea Analogues as Vanilloid Receptor Antagonists: Discovery of an N-Hydroxythiourea Analogue with Potent Analgesic Activity.​
     Lee, J.; Kang, S-U.; Choi, H-K.; Lee, J.; Lim, J-O.; Kil, M-J.; Jin, M-K.; Kim, K-P.; Sung, J-H.; Chung S-J.; Ha, H-J.; Kim, Y-H.; Pearce, L. V.; Tran, R.; Lundberg, D. J.; Wang, Y.; Toth, A.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry Letters 2004, 14(9), 2291-2297.​ Attachment file ; 74. BMCL 2004 2291-2297.pdf
115. Chain-branched 1,3-Dibenzylthioureas as Vanilloid Receptor 1 Antagonists. ​
     Ryu, C. H.; Jang, M. J.; Jung, J. W.; Park, J-H.; Choi, H. Y.; Suh, Y-G.; Oh, U.; Park, H-G.; Lee, J.; Koh, H-J.; Mo, J-H.; Joo, Y. H.; Park, Y-H.; Kim, H-D.
     Bioorganic & Medicinal Chemistry Letters 2004, 14(7) 1751-1755.​ Attachment file ; 73. BMCL 2004 1751-1755 Kim Heedoo.pdf
116. Synthesis of 70-[123I]iodo-D-luciferin for in vivo studies of firefly luciferase gene expression
     Lee, S-Y., Choe, Y. S., Lee, K-H., Lee, J., Choi, Y., Kim, B-T.
     Bioorganic & Medicinal Chemistry Letters 2004, 14(5), 1161-1163.​ Attachment file ; 72. BMCL 2004 1161-1163 Choe.pdf
117. ​Structure Activity Relationships of Simplified Resiniferatoxin Analogues with Potent VR1 Agonism Elucidates an Active Conformation of RTX for VR1 Binding. ​
     Lee, J.; Kim, S. Y.; Park, S.; Lim, J-O.; Kim, J-M.; Kang, M.; Lee, Ji.; Kang, S-U.; Choi, H-K.; Jin, M-K.; Welter, J. D.; Szabo, T.; Tran, R.; Pearce, L. V.; Toth, A.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry 2004, 12(5), 1055-1069​ Attachment file ; 71. BMC 2004 1055-1069.pdf
118. N-4-Substituted-benzyl-N’-tert-butylbenzyl Thioureas as Vanilloid Receptor Ligands: Investigation on the Role of Methanesulfonamido Group in Antagonistic Activity.​
     Park, H-G.; Choi, J-Y.; Choi, S-H.; Park, M-K.; Lee, J.; Suh, Y-G.; Cho, H.; Oh, U.; Lee, J.; Kang, S-U.; Lee, J.; Kim, H-D.; Park, Y-H.; Jeong, Y. S.; Choi, J. K.; Jew, S-S.
     Bioorganic & Medicinal Chemistry Letters 2004, 14(3), 787-791​​ Attachment file ; 70. BMCL 2004 787-791.pdf
119. ​Conformationally Constrained Diacylglycerol (DAG) Analogues: 4-C-Hydroxyethyl-5-O-Acyl-2,3-Dideoxy-D-Glyceropentono-1,4-Lactone Analogues as Protein Kinase C (PKC) Ligands.​
     Lee, J.; Kim, S. Y.; Kang, J-H.; Acs, G.; Acs, P; Blumberg, P. M.; Marquez, V. E.
     European Journal of Medicinal Chemistry 2004, 39(1), 69-77​ Attachment file ; 69. EJMC 2004 69-77.pdf
120. N-[4-(Methylsulfonylamino)benzyl]thiourea Analogues as Vanilloid Receptor Antagonists: Analysis of Structure Activity Relationships for the “C-Region”
     Lee, J.; Kang, S-U.; Lim, J-O.; Choi, H-K.; Jin, M-K.; Toth, A.; Pearce, L. V.; Tran, R.; Wang, Y.; Szabo, T.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry 2004, 12(2), 371-385​​ Attachment file ; 68. BMC 2004 371-385.pdf
121. SAR and Molecular Modeling of N-Benzyl-N-hydroxy-3-(cyclopentyloxy)-4-methoxybenzene carboxamide Analogues as Potent Phosphodiesterase-4 Inhibitors
     Lee, J.; Kim, S. Y.; Lee, H. R.; Kim, J. H.​
     Letters in Drug Design & Discovery 2004, 1, 19-23​ Attachment file ; 67. LDDD 2004 19-23.pdf
122. Novel Non-Vanilloid VR1 Antagonist of High Analgesic Effects and Its Structural Requirement for VR1 Antagonistic Effects.
     Suh, Y-G.; Lee, Y-S.; Min, K-H.; Park, O-H.; Seung, H-S.; Kim, H-D.; Park, H-G.; Choi,J-Y.; Lee, J.; S-W. Kang.; Oh, U-T.; Koo, J-Y.; Joo, Y-H.; Kim, S-Y.; Kim, J. K.; Park, Y-H.
     Bioorganic & Medicinal Chemistry Letters 2003, 13(24), 4389-4393.​ Attachment file ; 66. BMCL 2003 13 4389.pdf
123. 3D-QSAR Study and Molecular Docking of Methionyl-tRNA Synthetase Inhibitors 
     Kim, S. Y.; Lee, J.
     Bioorganic & Medicinal Chemistry 2003, 11(24), 5325-5331.​
     Attachment file ; 65. BMC 2003 5325.pdf
124. N-(3-Acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea Analogues: Novel Potent and High Affinity Antagonist and Partial Antagonists of the Vanilloid Receptor.
     Lee, J.; Lee, J.; Kang, M.; Shin, M-Y.; Kim, J-M.; Kang, S-U.; Lim, J-O.; Choi, H-K.; Suh, Y-G.; Park, H-G.; Oh, U.; Kim, H-D.; Park, Y-H.; Ha, H-J.; Kim, Y-H.; Toth, A.; Wang, Y.; Tran, R.; Pearce, L. V.; Lundberg, D. J.; Blumberg, P. M.
     Journal of Medicinal Chemistry 2003, 46(14) 3116-3126.​ Attachment file ; 64. JMC 2003 46, 3116.pdf
125. Conformationally Constrained Analogues of Diacylglycerol. 19 . Synthesis and Protein Kinase C (PK-C) Binding Affinity of DAG-Lactones Bearing an N-Hydroxylamide Side Chain
     Choi, Y.; Kang, J-H.; Lewin, N. E.; Blumberg, P. M.; Lee, J.; Marquez, V. E.
     Journal of Medicinal Chemistry 2003, 46(13), 2790-2793.​ Attachment file ; 63. JMC 2003 46, 2790.pdf
126. Conformationally Constrained Analogues of Diacylglycerol (DAG). Effect on Protein Kinase C (PK-C) Binding by the IsostericReplacement of sn-1 and sn-2 Esters in DAG-Lactones.
     Kang, J-H.; Chung, H-E.; Kim, S. Y.; Kim, Y.; Lee, J.; Lewin, N. E.; Pearce, L. V.; Blumberg, P. M.; Marquez, V. E. 
     Bioorganic & Medicinal Chemistry 2003, 11(12), 2529-2539.​ Attachment file ; 62. BMC 2003 11, 2529.pdf
127. High Affinity Partial Agonists of Vanilloid Receptor.
     Wang, Y.; Toth, A.; Tran, R.; Szabo, T.; Welter, J. D.; Blumberg, P. M.; Lee, J.; Kang, S-U.; Lim, J-O.; Lee, J. 
     Molecular Pharmacology 2003, 64(2), 325-333.​ Attachment file ; 61. Mol Pharm 2003 64, 325.pdf
128. N-Alkoxysulfamide, N-Hydroxysulfamide, and Sulfamate Analogues of Methionyl and Isoleucyl Adenylates as Inhibitors of Methionyl-tRNA and Isoleucyl-tRNA Synthetases.
     Lee, J.; Kim, S. E.; Lee, J. Y.; Kim, S. Y.; Kang, S. U.; Seo, S. H.; Chun, M. W.; Kang, T.; Choi, S. Y.; Kim, H. O. 
     Bioorganic & Medicinal Chemistry Letters 2003, 13(6), 1087-1092.​ Attachment file ; 60. BMCL 2003 13, 1087.pdf
129. Synthesis of N,N’,N”-Trisubstituted thiourea Derivatives and their Antagonist Effect on Vanilloid Receptor.
     Park, H-G.; Park, M-K.; Choi, J-Y.; Choi, S-H.; Lee, J.; Suh, Y-G.; Oh, U.; Lee, J.; Kim, H-D.; Park, Y-H.; Jeong, Y-S.; Choi, J-K.; Jew, S-S. 
     Bioorganic & Medicinal Chemistry Letters 2003, 13(4), 601-604.​ Attachment file ; 59. BMCL2003 13, 601.pdf
130. Lovastatin enhances Ab production and senile plaque deposition in female Tg2576 mice.
     Park, I-H.; Hwang, E. M.; Hong, H. S.; Boo, J. H.; Oh, S. S.; Lee, J.; Jung, M. W.; Bang, O. Y.; Kim, S. U.; Mook-Jung, I. H. 
     Neurobiology of Aging 2003, 24, 637-643.​ Attachment file ; 58. NBA 2003 24, 637.pdf
131. Synthesis of 2-Substituted-Pyrrolidine thiourea Derivatives and Their Antagonistic Effect on Vanilloid Receptor.
     Park, H-G.; Park, M-K.; Choi, J-Y.; Choi, S-H.; Lee, J.; Suh, Y-G.; Oh, U.; Lee, J.; Kim, H-D.; Park, Y-H.; Jeong, Y. S.; Choi, J. K.; Jew, S-S. 
     Bioorganic & Medicinal Chemistry Letters 2003, 13(2), 197-200.​ Attachment file ; 57. BMCL 2003 13, 197.pdf
132. High Affinity Antagonists of the Vanilloid Receptor.
     Wang, Y.; Szabo, T.; Welter, J. D.; Toth, A.; Tran, R.; Lee, J.; Kang, S. U.; Lee, Y-S.; Min, K. H.; Suh, Y-G.; Park, M-K.; Park, H-G.; Park, Y-H.; Kim, H-D.; Oh, U.; Blumberg, P. M.; Lee, J. 
     Molecular Pharmacology 2002, 62, 947-956. (Published erratum appears in Mol. Pharmacol. 2003, 63, 958)​ Attachment file ; 56. Mol Pharm 2002 62, 947.pdf
133. Inhibition of Mouse Skin Tumor Promotion by Anti-inflammatory Diarylheptanoids Derived from Alpinia Oxyphylla Miquel (Zingiberaceae)
     Chun, K-S.; Park, K-K.; Lee, J.; Kang, M.; Surh, Y-J. 
     Oncology Research 2002, 13, 37-55.​ Attachment file ; 55. Oncology Research 2002 13, 37-45.pdf
134. Conformationally Constrained Analogues of Diacylglycerol (DAG). 19. Asymmetric Syntheses of (3R)- and (3S)-3-Hydroxy-4,4-disubstituted heptono-1,4-lactones as Protein Kinase C (PK-C) Ligands with Increased Hydrophilicity.
     Nacro, K.; Lee, J.; Barchi, Jr. J. J.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Tetrahedron 2002, 58 (26), 5335-5345.​ Attachment file ; 54. Tetrahedron 2002 58, 5335.pdf
135. Phenolic Modification as an Approach to Improve the Pharmacology of the 3-Acyloxy-2-benzylpropyl Homovanillic Amides and Thioureas, a Promising Class of Vanilloid Receptor Agonist and Analgesics.
     Lee, J.; Lee, J.; Kang, M-S.; Kim, K-P.; Chung, S-J.; Blumberg, P. M.; Yi, J-B.; Park, Y. H. 
     Bioorganic Medicinal Chemistry 2002, 10(4), 1171-1179.​ Attachment file ; 53. BMC 2002 10, 1171.pdf
136. DAG-Lactones, a New Class of PKC Agonists, Induce Apotosis in LNCaP Prostate Cancer Cells by Selective Activation of PKCa.
     Garcia-Bermejo, M. L.; Leskow, F. C.; Fujii, T.; Wang, Q.; Blumberg, P. M.; Ohba, M.; Kuroki, T.; Han, K-C.; Lee, J.; Marquez, V. E.; Kazanietz, M. G. 
     Journal of Biological Chemistry 2002, 277(1), 645-655 Attachment file ; 52. JBC 2002 277, 645.pdf
137. Conformationally Constrained Analogues of Diacylglycerol 18. The Incorporation of a Hydroxamate Moiety into DAG-Lactones Reduces Lipophilicity and Helps Discriminate Between Sn-1 and Sn-2 Binding Modes to Protein Kinase C (PK-C), Implications for Isozyme Specificity.
     Lee, J.; Han, K-C.; Kang, J-H.; Pearce, L. L.; Lewin, N. E.; Yan, S.; Benzaria, S.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 2001, 44(25), 4309-4312. (Published erratum appears in J. Med. Chem. 2003, 46, 2794)​ Attachment file ; 51. JMC 2001 44, 4309.pdf
138. Comparative Study of Quantitative Structure Activity Relationship Methods Based on Antitumor Diarylsulfonylureas.
     Park Choo, H-Y.; Lim J-S.; Kam, Y.; Kim, S. Y.; Lee, J. A 
     European Journal of Medicinal Chemistry 2001, 36 (10), 829-836.​ Attachment file ; 50. EJMC 2001 36, 829.pdf
139. A Simple and Efficient in vitro Method for Metabolism Studies of Radiotracers.
     Lee, S-Y., Choe Y. S.; Kim, D. H.; Park, B-N.; Kim, S. E.; Choi, Y.; Lee, K-H.; Lee. J.; Kim B-T. 
     Nuclear Medicine and Biology 2001, 28 (4), 391-395.​ Attachment file ; 49. Nuclear Medicine and Biology 2002 28, 391.pdf
140. N-(3-Acyloxy-2-benzylpropyl)-N-Dihydroxy Tetrahydrobenzazepine and Tetrahydroisoquinoline Thiourea Analogues as Vanilloid Receptor Ligands.
     Lee, J.; Lee, J.; Szabo, T.; Gonzalez, A. F.; Welter, J. D.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry 2001, 9(7), 1713-1720. Attachment file ; 48. BMC 2001 9, 1713.pdf
141. 5-Acyloxy-5-hydroxymethyltetrahydro-2-furancarboxylate as a Novel Template for Protein Kinase C(PKC) Binding.
     Lee, J.; Han, K-C, Lee, S-Y, Kim, S-Y, Kang, J-H; Lewin, N. E.; Best, L. S.; Blumberg, P. M.; Marquez, V. E. 
     IL FARMACO 2001, 56(3), 203-210.​ Attachment file ; 47. FARMACO 2001 56, 203.pdf
142. Vanilloid and Isovanilloid Analogues as Inhibitors of Methionyl-tRNA and Isoleucyl-tRNA Synthetases. 
     Lee, J.; Kang, S. U.; Kim, S. Y.; Kim, S. E.; Jo, Y. J.; Kim, S. 
     Bioorganic & Medicinal Chemistry Letters 2001, 11(8), 965-968.​ Attachment file ; 46. BMCL 2001 11, 965.pdf
143. Ester and Hydroxamate Analogues of Methionyl and Isoleucyl Adenylates as Inhibitors of Methionyl-tRNA and Isoleucyl-tRNA Synthetases.
     Lee, J.; Kang, S. U.; Kim, S. Y.; Kim, S. E.; Kang, M. K.; Jo, Y. J.; Kim, S. 
     Bioorganic & Medicinal Chemistry Letters 2001, 11(8), 961-964.​ Attachment file ; 45. BMCL 2001 11, 961.pdf
144. N-(3-Acyloxy-2-benzylpropyl)-N’-(4-hydroxy-3-methoxybenzyl)thiourea Derivatives as Potent Vanilloid Receptor Agonists and Analgesics.
     Lee, J.; Lee, J.; Kim, J.; Kim, S. Y.; Chun, M. W.; Cho, H.; Hwang, S. W.; Oh, U.; Park, Y. H.; Marquez, V. E.; Beheshti, M.; Szabo, T.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry 2001, 9(1), 19-32.​ Attachment file ; 44. BMC 2001 9, 19.pdf
145. Synthesis and Biological Evaluation of 1-(4-[18F]Fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for In Vivo studies of Acetylcholinesterase.
     Lee, S-Y.; Y. S. Choe; H. Sugimoto, H.; Kim, S. E.; Hwang, S. H.; Lee, K-H.; Choi, Y.; Lee, J.; Kim, B-T. 
     Nuclear Medicine and Biology 2000, 27(8), 741-744.​ Attachment file ; 43. NMB 2000 27, 741.pdf
146. Analysis of Urinary S-Phenyl Mercapturic Acid and trans-trans-Muconic Acid for Exposure Biomarker of Benzene in Petrochemical and Industrial Area of Korea.
     Fang, M. Z.; Shin, M. K.; Park, K. W.; Kim, Y. S.; Lee, J.; Cho, M. H. 
     Scandinavian Journal of Work, Environment & Health 2000, 26(1), 62-66.​ Attachment file ; 42. Scan J 2000 26, 62.pdf
147. Conformationally Constrained Analogues of Diacylglycerol (DAG). 16. How Much Structural Complexity Is Necessary for Recognition and High Binding Affinity to Protein Kinase C
     Nacro, K.; Bienfait, B.; Lee, J.; Han, K-C.; Kang, J-H.; Benzaria, S.; Lewin, N. E.; Bhattacharyya, D. K.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 2000, 43(5), 921-944.​ Attachment file ; 41. JMC 2000 43, 921.pdf
148. Methionine analogue probes functionally improtant residues in active site of methionyl-tRNA synthetase.
     Y. J. Jo; S. W. Lee; M. K. Jo; J. Lee; M. K. Kang; J. H. Yoon; S. Kim 
     Journal of Biochemistry & Molecular Biology 1999, 32(6), 547-553​ Attachment file ; 40. J Biochem Mole 1999 32, 547.pdf
149. Facile and Practical Synthesis of Capsazepine, A Vanilloid Receptor Antagonist.
     Lee, J.; Lee, J. A 
     Synthetic Communication 1999, 29, 4127-4140.​ Attachment file ; 39. Syn comm 1999 29, 4127.pdf
150. Protein Kinase C Ligands Based on Tetrahydrofuran Templates Containing a New Set of Phorbol Ester Pharmacophores.
     Lee, J.; Kang, J-H.; Lee, S-Y.; Han, K-C.; Torres, C. M.; Bhattacharyya, D. K.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 1999, 42(20), 4129-4139.​ Attachment file ; 38. JMC 1999 42, 4129.pdf
151. 3-Acyloxy-2-phenalkylpropyl Amides and Esters of Homovanillic Acid as Novel Vanilloid Receptor Agonists.
     Lee, J.; Park, S-U., Kim, J-Y.; Kim, J-K., Lee, J.; Oh, U.; Marquez, V. E.; Beheshti, M.; Wang, Q. J.; Modarres, S.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry Letters 1999, 9(20), 2909-2914.​ Attachment file ; 37. BMCL 1999 9, 2909.pdf
152. Anti-tumor Promoting Potential of Naturally Occurring Diarylheptanoids Stucturally Related to Curcumin.
     Chun, K-S; Sohn, Y.; Kim, H-S; Kim, O-H; Park, K-K; Lee, J-M; Lee, J.; Lee, J-Y; Moon, A.; Lee, S- S; Surh, Y-J. 
     Mutation Research 1999, 428, 49-57.​ Attachment file ; 36. Mutation Research 1999 428, 49.pdf
153. The Transition from a Pharmacophore-Guided Approach to a Receptor-Guided Approach in the Design of Potent Protein Kinase C Ligands.
     Marquez, V. E.; Nacro, K.; Benzaria, S.; Lee, J.; Sharma, R.; Teng, K.; Milne, G. W. A.; Bienfait, B.; Wang, S.; Lewin, N. E.; Blumberg, P. M. 
     Pharmacology and Therapeutics 1999, 82(2), 251-261.​ Attachment file ; 35. Pharm Ther 1999 82, 252.pdf
154. Methionyl Adenylate Analogues as Inhibitors of Methionyl-tRNA Synthetase.
     Lee, J.; Kang, S. U.; Kang, M. K.; Chun, M. W.; Jo, Y. J.; Kwak, J. H.; Kim, S. 
     Bioorganic & Medicinal Chemistry Letters 1999, 9(10), 1365-1370.​ Attachment file ; 34. BMCL 1999, 9, 1365.pdf
155. Methionine Analogues as Inhibitors of Methionyl-tRNA Synthetase.
     Lee, J.; Kang, M. K.; Chun, M. W.; Jo, Y. J.; Kwak, J. H.; Kim, S. 
     Bioorganic & Medicinal Chemistry Letters 1998, 8(24), 3511-3514.​ Attachment file ; 33. BMCL 1998 8, 3511.pdf
156. Conformationally Constrained Analogues of Diacylglycerol (DAG) 14. Dissection of the Roles of the sn-1 and sn-2 Carbonyls in DAG Mimetics by Isopharmacophore Replacement.
     Marquez, V. E.; Sharma, R.; Wang, S.; Lewin, N. E.; Blumberg, P. M.; Kim, I-S, Lee, J. 
     Bioorganic & Medicinal Chemistry Letters 1998, 8(13), 1757-1762.​ Attachment file ; 32. BMCL 1998 8, 1757.pdf
157. Design and Synthesis of Bioisosteres of Ultrapotent Protein Kinase C (PKC) Ligand, 5-Acetoxymethyl-5-Hydroxymethyl-3-Alkylidene Tetrahydro-2-furanone.
     Lee, J. 
     Archives of Pharmacal Research 1998, 21(4), 452-457.​ Attachment file ; 31. APR 1998 21, 452-457.gif
158. Synthesis and Biological Activity of 5-Hydroxy-4-Quinolones and 5-Methoxy-4-Quinolones as Truncated Acridones.
     Chun, M. W.; Olmstead, K. K.; Choi, Y. S.; Lee, C. O.; Lee, C. K.; Kim, J. H.; Lee, J. 
     Archives of Pharmacal Research 1998, 21(4), 445-451.​ Attachment file ; 30. APR 1998 21, 445-451.gif
159. ​​Conformationally Constrained Analogues of Diacylglycerol Having a Perhydrofuro [3,4-c]furan-1,4-dione Bis-g-Butyrolactone Skeleton.
     Lee, J.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Archives of Pharmacal Research 1998, 21(2), 164-167.​ Attachment file ; 29. APR 1998 164-167.gif
160. Conformationally Constrained Analogues of Diacylglycerol: Protein Kinase C (PK-C) Ligands Based on a 5-Disubstituted Tetrahydro-2-Furanone Having an (R)-Hydroxyethyl Group.
     Lee, J.; Jeong, S. H.; Chun, M. W.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Carbohydrate Letters 1997, 2(6), 307-312.​ Attachment file ; 28. Carbohydrate Letter 1997 2, 307.pdf
161. Synthesis and Antiviral Activities of 1,3-Dioxolanyl-, 1,3-Oxathiolanyl- and 1,3-Dithiolanylnucleosides with 2-Hydroxymethyl Substituents.
     Chun, M. W.; Shin, D. H.; Moon, H. R.; Lee, J.; Park, H.; Jeong L. S. 
     Bioorganic & Medicinal Chemistry Letters 1997, 7, 1475-1480.​ Attachment file ; 27. BMCL 1997 7, 1475.pdf
162. Synthesis and Biological Activities of Truncated Acridone: Structure-Activity Relationship Studies of Cytotoxic 5-Hydroxy-4-Quinolone.
     Chun, M. W.; Olmstead, K. K.; Choi, Y. S.; Lee, C. O.; Lee, C. K.; Kim, J. H.; Lee, J. 
     Bioorganic & Medicinal Chemistry Letters 1997, 7, 789-792.​ Attachment file ; 26. BMCL 1997 7, 789.pdf
163. Synthesis and Antiviral Activity of Fluoro Sugar Nucleosides 2: Synthesis and Biological Evaluations of 2',3'-Dideoxy-2'-Fluoro-3'-C-Hydroxymethyl-b-D-Arabino furanosyl Nucleosides.Chun, M. W.; Lee, K.; Choi, Y. S.; Lee, J.; Kim, J. H.; Lee, C. K.; Choi, B. G.; Xu, Y. C. S
     Archives of Pharmacal Research 1996, 19(3), 243-245.​ Attachment file ; 25. APR 1996 19, 243-245.gif
164. Conformationally Constrained Analogues of Diacylglycerol. 13. Protein Kinase C Ligands Based on Templates Derived from 2,3-Dideoxy-L-erythro(threo)-hexono-1,4-lactone and 2-Deoxyapiolactone.
     Lee, J.; Lewin, N. E.; Acs, P.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 1996, 39(25), 4912-4919.​ Attachment file ; 24. JMC 1996 39, 4912.pdf
165. Synthesis of bis-g-Butyrolactones Containing Conformationally Constrained (S)- and (R)-Diacylglycerol Structures.
     Lee, J.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Bioorganic & Medicinal Chemistry 1996, 4(8), 1299-1305.​ Attachment file ; 23. BMC 1996 4, 1299.pdf
166. Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes.
     Acs, G.; Lee, J.; Marquez, V. E.; Blumberg, P. M. 
     Molecular Brain Research 1996, 35, 173-182.​ Attachment file ; 22. MBR 1996 35, 173.pdf
167. Conformationally Constrained Analogues of Diacylglycerol. 12. Ultrapotent Protein Kinase C Ligands Based on a Chiral 5-Disubstituted Heptono-1,4-Lactone Template.
     Lee, J.; Sharma, R.; Wang, S.; Milne, G. W. A.; Lewin, N. E.; Szallazi, Z.; Blumberg, P. M.; George, C.; Marquez, V. E. 
     Journal of Medicinal Chemistry 1996, 39(1), 36-45.​ Attachment file ; 21. JMC 1996 39, 36.pdf
168. Conformationally Constrained Analogues of Diacylglycerol. 11. Ultrapotent Protein Kinase C Ligands Based on a Chiral 5-Disubstituted Tetrahydro-2-furanone Template.
     Lee, J.; Wang, S.; Milne, G. W. A.; Sharma, R.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 1996, 39 (1), 29-35.​ Attachment file ; 20. JMC 1996 39, 29.pdf
169. Conformationally Constrained Analogues of Diacylglycerol (DAG). 10. Ultrapotent Protein Kinase C (PK-C) Ligands Based on a Racemic 5-Disubstituted Tetrahydro-2-furanone Template.
     Sharma, R.; Lee, J.; Wang, S.; Milne, G. W. A.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Journal of Medicinal Chemistry 1996, 39 (1), 19-28.​ Attachment file ; 19. JMC 1996 39, 19.pdf
170. Thiourea Analogues of Resiniferatoxin as Ligands for the Vanilloid Receptor.
     Lee, J.; Acs, G.; Blumberg, P. M.; Marquez, V. E. 
     Bioorganic & Medicinal Chemistry Letters 1995, 5 (13), 1331-1334.​ Attachment file ; 18. BMCL1995 5, 1331.pdf
171. Design and Synthesis of Heterocyclic Analogues of Mycophenolic Acid as Potential Chemotherapeutic Agents.
     Lee, J.; Anderson, W. K. 
     Bioorganic & Medicinal Chemistry Letters 1995, 5 (8), 861-866.​ Attachment file ; 17. BMCL1995 5, 861.pdf
172. Synthesis of Chiral Doubly C-4 Branched γ-Lactones. An Efficient Synthesis of 4-C-Hydroxymethyl-2,3-Dideoxy-Hexono-1,4-Lactones.
     Lee, J.; Sharma, R.; Marquez, V. E. 
     Carbohydrate Letters 1995, 1, 285-290.​ Attachment file ; 16. Carbohydrate Letter 1995 1, 285.pdf
173. Synthesis of A Rigid Diacylglycerol Analogue Having a Bis-g-Butyrolactone Skeleton Separated by a Cyclopentane Ring.
     Lee, J.; Barchi, Jr. J. J.; Marquez, V. E. 
     Chemistry Letters 1995, 299-300. Attachment file ; 15. Chem Lett 1995 299.pdf
174. Acs, G.; Lee, J.; Marquez, V. E.; Wang, S.; Milne, G. W. A.; Lewin, N. E.; Blumberg, P. M. 
     Resiniferatoxin-Amide and Analogues as Ligands for Protein Kinase C and Vanilloid Receptor and Determination of Their Biological Activities as Vanilloids
     Journal of Neurochemistry 1995, 65, 301-308. Attachment file ; 14. J Neurochem 1995 65, 301.pdf
175. Conformationally Constrained Analogues of Diacylglycerol (DAG). 9. The Effect of Side-Chain Orientation on the Protein Kinase C (PK-C) Binding Affinity of d-Lactones
     Lee, J.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Bioorganic & Medicinal Chemistry Letters 1994, 4 (20), 2405-2410.​ Attachment file ; 13. BMCL 1994 4, 2405.pdf
176. Conformationally Constrained Analogues of Diacylglycerol (DAG). 8. Changes in PK-C Binding Affinity Produced by Isosteric Group of the 3-O-Acyl Function in 2-Deoxy-L-Ribonolactones.
     Lee, J.; Sharma, R.; Teng, K.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. 
     Bioorganic & Medicinal Chemistry Letters 1994, 4 (11), 1369-1374.​ Attachment file ; 12. BMCL 1994 4, 1369.pdf
177. Protein Kinase C. Modeling of the Binding Site and Prediction of Binding Constants.
     Wang, S.; Milne, G. W. A.; Nicklaus, M. C.; Marquez, V. E.; Lee, J.; Blumberg, P. M. 
     Journal of Medicinal Chemistry 1994, 37 (9), 1326-1338.​ Attachment file ; 11. JMC 1994 37, 1326.pdf
178. Synthesis of Two Rigid Diacylglycerol Analogues Having a 1,7-Dioxaspiro[4,4]nonane Bis-g-lactone Skeleton. 4.
     Lee, J.; Marquez, V. E.; Lewin, N.; Blumberg, P. M. 
     Synlett 1994, 4 (3), 206-208. Attachment file ; 10. Synlett 1994 4, 206.pdf
179. Conformationally Constrained Analogues of Diacylglycerol (DAG). 7. Interaction of a Medium-Size e-Lactone with Protein Kinase C (PK-C).
     Lee, J.; Marquez, V. E.; Lewin, N.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry Letters 1994, 4 (4), 543-548.​ Attachment file ; 9. BMCL 1994 4, 543.pdf
180. Conformationally Constrained Analogues of Diacylglycerol (DAG). 6. Changes in PK-C Binding Affinity for 3-O-Acyl-2-Deoxy-L-Ribonolactones Bearing Different Acyl Chains.
     Marquez, V. E.; Lee, J.; Sharma, R.; Teng, K.; Wang, S.; Lewin, N.; Blumberg, P. M. 
     Bioorganic & Medicinal Chemistry Letters 1994, 4 (2), 355-360.​ Attachment file ; 8. BMCL 1994 4, 355.pdf
181. Synthesis of Two Rigid Diacylglycerol Analogues Having a Perhydrofuro[3,2-b]furan Bis-γ-Butyrolactone Skeleton 3.
     Lee, J.; Marquez, V. E.; Bahador, A.; Kazanietz, M. G.; Blumberg, P. M. 
     Tetrahedron Letters 1993, 34 (27), 4317-4320.​ Attachment file ; 7. TL 1993 34, 4317.pdf
182. Synthesis of Two Rigid Diacylglycerol Analogues Having a Perhydrofuro[3,4-b]furan Bis-γ-Butyrolactone Skeleton 2.
     Lee, J.; Marquez, V. E.; Lewin, N. E.; Blumberg, P. M. 
     Tetrahedron Letters 1993, 34 (27), 4313-4316.​ Attachment file ; 6. TL 1993 34, 4313.pdf
183. Conformationally Constrained Analogues of Diacylglycerol (DAG). 4. Interaction of α-Alkylidene-γ-Lactones with Protein Kinase C (PK-C)
     Lee, J.; Marquez, V. E.; Lewin, N. E.; Kazanietz, M. G.; Bahador, A.; Blumberg, P. M.
     Bioorganic & Medicinal Chemistry Letters 1993, 3 (6), 1107-1110.​ Attachment file ; 5. BMCL 1993 3, 1107.pdf
184. Conformationally Constrained Analogues of Diacylglycerol (DAG). 3. Interaction of α-Alkyl-γ-Lactones with Protein Kinase C (PK-C)
     Lee, J.; Marquez, V. E.; Lewin, N. E.; Kazanietz, M. G.; Bahador, A.; Blumberg, P. M.   
     Bioorganic & Medicinal Chemistry Letters 1993, 3 (6), 1101-1106​ Attachment file ; 4. BMCL 1993 3, 1101.pdf
185. Conformationally Constrained Analogues of Diacylglycerol(DAG).2.
     Differential Interaction of γ-Lactones and δ-Lactones with Protein Kinase C(PK-C)
     Lee, J.; Marquez, V. E.; Blumberg, P. M.; Krausz, K. W.; Kazanietz, M. G.
     Bioorganic & Medicinal Chemistry 1993, 1 (2), 119-123. Attachment file ; 3. BMC 1993 1, 119.pdf
186. Synthesis of Two Rigid Diacylglycerol Analogues Having a Bis-Butyrolactone Skeleton.
     Lee, J.; Teng,K; Marquez, V. E.
     Tetrahedron Letters 1992, 33 (12), 1539-1542. Attachment file ; 2. TL 1992 33, 1539.pdf
187. A Facile Synthesis of an (E)-4-Methyl-4-Hexenoic Acid Substituted Pyridine Analogue of Mycophenolic Acid.
     Lee, J.; Anderson, W. K.
     Synthetic Communication 1992, 22 (3), 369-376. Attachment file ; 1. Syn Comm 1992 22, 369.pdf

Invited Review Articles